Description
Isotroin 20 MG Capsule belongs to a category of chemical compounds called retinoid. This medication helps in the treatment of cystic acne or nodular acne that has previously not responded to any other kinds of treatment. It lowers the production of facial oil and prevents hardening of the skin. If acne is not properly treated it can cause permanent scarring.
The dosage and the drug form depend on the age, weight and medical condition of an individual. Use Isotretinoin as prescribed by your doctor. It is available in tablet, capsule, or gel dosage forms.
- Swallow the tablet/capsule whole. Do not crush or chew the tablet/capsule. Take Isotretinoin with food.
- Apply Isotretinoin gel over the acne.
The overdose symptoms of Isotretinoin may include:
- Difficulty in breathing
- Facial flushing
- Headache
- Loss of balance
Allergy
This medicine is not recommended for use if you have a known history of allergy to tretinoin/isotretinoin/retinoids or any other component present in the dosage form.
Liver disease
This medicine is not recommended for use if you have an impairment of liver function.
Hypervitaminosis A
This medicine is not recommended for use if you have more than normal levels of vitamin A in the body.
Take isotretinoin exactly as your doctor tells you to. There are several strengths of isotretinoin capsules available: 5 mg, 10 mg, 20 mg, and 40 mg. Your dose will be calculated from your weight each dose may be a combination of different strengths of capsule.
Isotretinoin is taken once or twice each day. Your doctor will tell you how many capsules of which strengths to take for each dose, and what time(s) of the day to take the doses. This information will also be printed on the label of the packs to remind you about what the doctor said to you.
Take the capsules with food; during a meal is ideal. It is best to swallow the capsules with a drink of water. Do not open or chew the capsules.
If your doctor thinks it necessary, your dose may be adjusted during the course of your treatment. If this happens, make sure you follow carefully the instructions that your doctor gives to you.
You will be prescribed a course of treatment that lasts for 4-6 months. Only one course of treatment is usually needed.
If you forget to take a dose, take it as soon as you remember (unless it is nearly time for your next dose, in which case take the next dose when it is due and leave out the forgotten dose). Do not take two doses together to make up for a missed dose.
Allergy
This medicine is not recommended for use if you have a known history of allergy to tretinoin/isotretinoin/retinoids or any other component present in the dosage form.
Liver disease
This medicine is not recommended for use if you have an impairment of liver function.
Hypervitaminosis A
This medicine is not recommended for use if you have more than normal levels of vitamin A in the body.
Missed Dose
Skip the missed dose and continue with the regularly scheduled dose. Do not take extra medicine to make up for the missed dose.
Overdose
Contact a doctor immediately if an overdose with this medicine is suspected. Symptoms of overdose may include a headache, dizziness, vomiting, stomach pain, tingling and stinging sensation of the skin etc.
Dry lips and mouth, minor swelling of the eyelids or lips, crusty skin, nosebleeds, upset stomach, or thinning of hair may occur.
If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water, or use a saliva substitute.
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Preexisting Or Predisposition To Hypertriglyceridaemia (E.G. DM, Obesity Or Increased Alcohol Intake). Monitor Triglyceride Levels. Monitor Blood Lipids And LFTs At Wkly Or Bi-Wkly Intervals. Monitor Blood Glucose In Known Or Suspected DM Patients.
Genetic Predisposition For Age-Related Osteoporosis, History Of Childhood Osteoporosis, Osteomalacia Or Other Bone Metabolism Disorders. Anorexia Nervosa. History Of Psychiatric Disorder. May Impair Night Vision. Avoid Wax Epilation And Skin Resurfacing Procedures For At Least 6 Mth. Avoid Prolonged Exposure To UV Light Or Sunlight. Discontinue If Hearing Impairment, Abdominal Pain, Rectal Bleeding, Severe Diarrhoea Or Adverse Ocular Effects Occur. Patient Should Not Donate Blood During Therapy And For At Least 1 Mth Following Drug Discontinuation.
[Internet]. 2017 [cited 8 May 2017]. Available from: https://www.medicines.org.uk/emc/medicine/15655
DailyMed – isotretinoin capsule [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 8 May 2017]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3ef0cff8-19c1-4441-b780-fca6c7ee1615
Isotretinoin – DrugBank [Internet]. Drugbank.ca. 2017 [cited 8 May 2017]. Available from: https://www.drugbank.ca/drugs/DB00982
Isotretinoin: MedlinePlus Drug Information [Internet]. Medlineplus.gov. 2017 [cited 16 November 2017]. Available from: https://medlineplus.gov/druginfo/meds/a681043.html
1. Is it safe to alter the dose of Isotretinoin?
No. It is not safe to change the dose of Isotretinoin unless suggested by the doctor.
2.Is it safe to use Isotretinoin in patients with a history of osteoporosis?
No. Isotretinoin is not safe to use in patients with a history of osteoporosis.
3.Should I follow any special dietary instructions while using Isotretinoin tablet?
Isotretinoin is a derivative of vitamin A. Therefore, avoid foods rich in vitamin A as it may worsen the side effects of Isotretinoin.
4.How long does Isotretinoin tablet take to show its effect?
A complete clearing of acne may be achieved within 16 to 24 days of continued treatment.
5.Is it safe to use Isotretinoin in patients with glaucoma?
No. Use of Isotretinoin should be avoided in patients with glaucoma.
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