Lopimune Tablet

Lopimune Tablets are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over and children over 6 months. Lopinavir 20mg and ritonavir 50mg are antiviral medications that prevent human immunodeficiency virus (HIV) cells from multiplying in your body. This drugs are used in combination with other medications that have a different mechanism of action to the components in Lopimune, and are used to treat patients with HIV infection who have either already received treatment with other medications for HIV or as first line therapy for treatment-inexperienced patients. 

Lopimunecontains two active ingredients Lopinavir and Ritonavir.  It is mainly used to treat people with human immunodeficiency virus (HIV) infection. You can buy Lopimuneonline also.

This medication is an HIV-1 protease inhibitor which is used in combination with other antiretroviral agents for HIV-1 infection treatment in adults and paediatric patients 14 days and older.

Lopimune Tablet is used for Rocky mountain spotted fever, Bacterial infection of the eye, Urinary tract infection, Hiv, Aids and other conditions. Lopimune Tablet may also be used for purposes not listed in this medication guide.

Lopimune Tablet contains Lopinavir and Ritonavir as active ingredients. Lopimune Tablet works by inhibiting the viral particles growth; preventing virus from multiplying inside the body;

Lopimune tablets 200/50mg are a fixed dose combination treatment for Human Immunodeficiency Virus (HIV) infection in adults over and children over 6 months.

Lopimune tablets200/50mg are used in combination with other medications that have a different mechanism of action to the components in Lopimune, and are used to treat patients with HIV infection who have either already received treatment with other medications for HIV or as first line therapy for treatment-inexperienced patients.

HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful); also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS).

Lopimune tablets prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level and this results in an increase in CD4+ cell numbers, so that the immune system can recover, reducing the risk of disease progression.

Lopimune 50mg/200mg Tablet is a combination of two anti-HIV medicines: Ritonavir and Lopinavir. They work by interfering with an enzyme (protease), which is required by HIV-infected cells to make new viruses. This stops the production of new viruses.

You should continue to take your Lopimune tablets 200/50mg regularly for as long as your doctor recommends as it helps control the HIV infection but does not cure it; do not stop taking your tablets even if you feel better without discussion with your doctor.

Lopimune is contraindicated in patients with previously demonstrated clinically significant hypersensitivity (e.g. toxic epidermal necrolysis, Stevens-Johnson syndrome, erythema multiforme, urticaria, angioedema) to any of its ingredients, including ritonavir.

Co-administration of Lopimune is contraindicated with drugs that are highly dependent on CYP3A for clearance and for which elevated plasma concentrations are associated with serious and/or life-threatening reactions.

Co-administration of Lopimune is contraindicated with potent CYP3A inducers where significantly reduced lopinavir plasma concentrations may be associated with the potential for loss of virologic response and possible resistance and cross-resistance

• Missed Dose:

If you miss a dose of Lopimune tablets Lopinavir 200mg + Ritonavir 50mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

• Overdose:

Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects.

If you suspect that you or anyone else who may have overdosed of Lopimune Tablet, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.

Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage. Please consult your physician or pharmacist or product package for more information.

You may encounter some normal and transitory symptoms, for example, Rash, Headache, Dizziness, Muscle torment, Insomnia (trouble in resting), Vomiting, Weakness, Nausea, Abdominal agony, Loss of hunger, Dyspepsia, Circumoral paresthesia, Paresthesia (shivering or pricking sensation), Glucose bigotry, Jaundice, Fatigue, Fever, Incresed blood lipid level, Diarrhea, Peripheral neuropathy (shivering and deadness of feet and hand), Depression, Feeling of uneasiness, Altered taste, Increased cholesterol level in blood, Increased triglyceride level in blood, Increased glucose level in blood.

Alcohol

Interaction with alcohol is unknown. Please consult your doctor.

Pregnancy

Lopimune 50mg/200mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.

Lactation

Lopimune 50mg/200mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.

Driving

It is not known whether Lopimune 50mg/200mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney

Lopimune 50mg/200mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Lopimune 50mg/200mg Tablet may not be needed in these patients. Please consult your doctor

Liver

Lopimune 50mg/200mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Lopimune 50mg/200mg Tablet may be needed. Please consult your doctor.

J Acquir Immune Defic Syndr. 2007 May 1;45(1):4-8. HIV-infected patients receiving lopinavir/ritonavir-based antiretroviral therapy achieve high rates of virologic suppression despite adherence rates less than 95%. https://www.ncbi.nlm.nih.gov/pubmed/17460469… – Accessed: October 12, 2016.

Achan J, Kahuru A, Ikilezi G, Ruel T, Clark T, Charlebois E, Rosenthal P, Dorsey G, Havlir D, Kamya M. Significant reduction in risk of malaria among HIV+ children receiving lopinavir/ritonavir-based ART compared to NNRTI-based ART, a randomized open-label trial. Abstract presented at CROI

Dailymed LABEL: NORVIR- ritonavir capsule https://dailymed.nlm.nih.gov/dailymed/dr… – Accessed: October 12, 2016. (Accessed on 2/11/17)

1.Is ritonavir safe during pregnancy?

Ritonavir can be taken during pregnancy if the benefit outweighs the risk.

2.Is ritonavir safe during breastfeeding?

Ritonavir is not safe for the baby and should not be used by women who are breastfeeding. HIV infected women should not breast-feed as the virus can pass on to the baby from breast milk.

3.Is ritonavir a protease inhibitor? What is ritonavir used for?

Ritonavir, a protease inhibitor, is used along with other medication for treating human immunodeficiency virus (HIV) infection. It does not completely cure HIV or AIDS. Lopinavir

4.Is Lopinavir safe during pregnancy?

Lopinavir should only be used if the potential benefits justify the potential risk to the baby. Please follow your doctor’s advice regarding its use.

5.Is Lopinavir safe during breastfeeding?

Lopinavir should be given only if the potential benefit justifies the potential risk to the infant. Please follow your doctor’s advice regarding its use.