Susten 400mg Capsule

What is Susten 400 mg Capsule?

Susten 400 Capsule is used for Recurrent miscarriage, Absence of a menstrual period, Uterine bleeding, Recurrent abortion, Recurrent miscarriage, amenorrhoea, abnormal uterine bleeding, palliative treatment of advanced, inoperable endometrial carcinoma, Progesterone stimulates luteal actions, changes in uterus and vagina as seen in early pregnancy. Susten 400 Capsule may also be used for purposes not listed in this medication guide.

Susten 400 Capsule contains Progesterone as an active ingredient. Susten 400 Capsule works by stimulates luteal actions, changes in uterus and vagina. Sun Pharma manufactures Susten 400 Capsule.

Susten 400 mg Capsule Uses?

Susten 400mg Soft Gelatin Capsule is used in the treatment of female infertility and hormone replacement therapy. It is also used to restore menstruation in women with secondary amenorrhea (the absence of menstrual cycles).

How does Susten 400 mg Capsule work?

Susten 400mg Soft Gelatin Capsule is a progesterone (female hormone). It works on the lining of the uterus and helps to establish and maintain pregnancy in infertile women. It helps in protecting the uterus from the negative effects of estrogen when used for the treatment of postmenopausal symptoms.

How to take Susten 400 mg Capsule?

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Susten 400mg Soft Gelatin Capsule is to be taken with food.

Susten 400 mg Capsule Contraindications:

Allergy

This medicine is not recommended for use if you have a known history of allergy to progesterone or any other ingredient present with it. This medicine might contain peanut oil and should never be used by patients who are allergic to peanuts.

 Abnormal vaginal bleeding

This medicine is not recommended for use if you have an abnormal bleeding episode which has not been diagnosed by a doctor.

 Breast cancer

This medicine is not recommended for use if you have breast cancer or are suspected to have it. It is not recommended for use if the patient has a history of breast cancer.

 Miscarriage

This medicine is not recommended for use if the patient has had an incomplete miscarriage or missed abortion recently.

 Heart and blood vessel disorder

This medicine is not recommended for use in patients having an active or historic instance of stroke or heart attack. It should not be used by patients having an active or historic clotting disorder.

 Liver disease

This medicine is not recommended for use in patients having a liver disease or impairment of normal liver function.

 Pregnancy

This medicine is not recommended for use if you are pregnant or are suspecting a pregnancy.

Susten 400 mg Capsule Dosage:

Missed Dose

Take the missed dose as soon as you remember unless it is almost time for the next scheduled dose. Contact your doctor if you have missed more than one dose.

Overdose

Contact your doctor if an overdose is suspected. The short-term effects of an overdose could be a headache, dizziness, nausea, and vomiting.

What are the Side effects of Susten 400 mg Capsule?

The most commonly reported side-effects of Susten 400 Capsule are progestins can cause masculinization of female foetus, cough, breast engorgement, headache, rise in body temperature, and edema.

The following is a list of possible side effects that may occur from the use of Susten 400 Capsule. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

• Progestins can cause masculinization of female foetus
• Cough
• Breast engorgement
• Headache
• Rise in body temperature
• Edema
• Esophageal reflux
• Acne
• Mood swings may occur
• Irregular bleeding or amenorrhoea
• Long term use of progestin in hormone replacement therapy may increase the risk of breast cancer
• Blood sugar may rise
• Diabetes may be precipitated by long-term use of potent agents
• Levonorgestrel

Susten 400 mg Capsule Warnings?

Pregnancy

This medicine is recommended for use in pregnancy only if the need is clinically established. Consult your doctor before using this medicine.

Breast-feeding

Use of this medicine is not recommended if you are breastfeeding. This medicine can pass into the breast milk and may harm the nursing infant.

General warnings

Dizziness

Use of this medicine can cause dizziness and impair the ability to perform tasks requiring cognition and alertness. Caution is advised while driving or performing other tasks that demand a high level of mental alertness. You are advised to take the medicine at recommended times to avoid any such effect.

Breast cancer

Use of this medicine in conjugation with estradiol for hormone replacement therapy has been associated with instances of breast cancer and hence caution is advised. This medicine should be given with extreme caution to patients with a previous or active case of breast cancer.

Blood clotting disorders

Use of this medicine is not recommended for patients having a clotting disorder. It is advised to undergo a test to confirm if the medicine can be safely used. Report any instance of such disease to the doctor.

Bleeding disorders

Use of this medicine is not recommended if you have severe undiagnosed vaginal bleeding.

Fluid retention

Use of this medicine is known to cause mild to moderate amounts of fluid retention in the body. Hence, caution is advised while administering in patients with diseases like epilepsy, asthma, migraine, heart and blood vessel disorders, kidney impairment etc.

 References:

[Internet]. 2017 [cited 5 October 2017]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/019781s013lbl.pdf

[Internet]. 2017 [cited 4 April 2017]. Available from: http://www.medsafe.govt.nz/profs/Datasheet/u/UtrogestanSunflowerOilcap.pdf

DailyMed – Crinone- progesterone gel [Internet]. Dailymed.nlm.nih.gov. 2017 [cited 4 April 2017]. Available from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=2c8ffbd2-6b7a-42c7-b29e-e4de69dad9e6

[Internet]. 2017 [cited 5 October 2017]. Available from: http://www.ferringusa.com/wp-content/uploads/2016/09/EndometrinPI-9.2016.pdf

Luteal Phase Support in assisted reproductive technology treatment: focus on Endometrin® (progesterone) vaginal insert [Internet]. PubMed Central (PMC). 2017 [cited 5 October 2017]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2695240/

FAQ:

1.What are the contraindications of SUSTEN 400mg Capsule?

SUSTEN 400mg Capsule is contraindicated in patients with myocardial infarction, venous thromboembolism, pulmonary embolism and retinal thrombosis.

2.Is SUSTEN 400mg Capsule used in hormone replacement therapy?

Yes. SUSTEN 400mg Capsule is used in hormone replacement therapy to decrease the symptoms of menopause.

3.Does lack of SUSTEN 400mg Capsule cause polycystic ovary syndrome (PCOS)?

Yes, lack of SUSTEN 400mg Capsule causes polycystic ovary syndrome (PCOS), due to the failure of the ovary to release the egg.

4.Should I follow any special dietary instructions while taking SUSTEN 400mg Capsule?

It is advised to avoid caffeinated foods, such as coffee and tea and increase a diet rich in magnesium, folate and vitamin supplements while taking SUSTEN 400mg Capsule.